Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA7 | P43166 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL93296 | 0.89 | CA1 (0.52) | CA1CA2CA7ALDH1A1LMNA | |
| Glycerin SCHEMBL9617071 | 0.89 | CA1 (0.52) | CA1CA2CA7ALDH1A1LMNA | |
| Glycerin SCHEMBL748344 | 0.89 | CA1 (0.52) | CA1CA2CA7ALDH1A1LMNA | |
| Glycerin SCHEMBL525782 | 0.89 | CA1 (0.52) | CA1CA2CA7ALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL952926 | 0.88 | CA1 (0.55) | CA1CA2CA7CA9CA4 | |
| Glycerin SCHEMBL27478437 | 0.88 | CA1 (0.41) | CA1CA2CA7ALDH1A1LMNA | |
| Glycerin SCHEMBL5925037 | 0.87 | CA1 (0.50) | CA1CA2CA7ALDH1A1LMNA | |
| Glycerin SCHEMBL7868615 | 0.87 | CA1 (0.50) | CA1CA2CA7ALDH1A1LMNA | |
| Glycerin SCHEMBL5924822 | 0.87 | CA1 (0.50) | CA1CA2CA7ALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL9475257 | 0.86 | CA1 (0.53) | CA1CA2CA7CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156721-A | Use of anionic gemini tensides in formulations for washing, cleaning and body care agents | RWE-DEA AKTIENGESELLSCHAFT FUER MINERALOEL UND CHEMIE (DE) | 2000-12-05 | — | — | US | claimed |
| EP-0915945-B1 | FORMULATIONS FOR WASHING, CLEANING AND BODY CARE AGENTS COMPRISING ANIONIC GEMINI SURFACTANTS AND THEIR USE | RWE DEA AG (DE) | 2000-10-11 | — | — | EP | claimed |
| CN-1093877-C | Use of anionic gemini tensides in formulations for washing, cleaning and body care agents | RWE DEA PETROCHEMICAL CO LTD (DE) | 2002-11-06 | — | — | CN | disclosed |
| US-6156721-A | Use of anionic gemini tensides in formulations for washing, cleaning and body care agents | RWE-DEA AKTIENGESELLSCHAFT FUER MINERALOEL UND CHEMIE (DE) | 2000-12-05 | — | — | US | disclosed |
| US-6034271-A | Betaine gemini surfactants made from amines | HUELS AKTIENGESELLSCHAFT (DE) | 2000-03-07 | — | — | US | disclosed |
| CN-1222932-A | Use of anionic gemini surfactants in formulations of detergents, cleaning agents and skin-care agents | RWE DEA PETROCHEMICAL CO LTD (DE) | 1999-07-14 | — | — | CN | disclosed |
| CN-1173127-A | Shelf stable skin cleansing liquid compositions containing gel forming polymers and lipids | PROCTER & GAMBLE (US) | 1998-02-11 | — | — | CN | disclosed |