Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27952255 | 0.74 | PIK3CB (0.41) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL19929 | 0.74 | — | — | |
| SCHEMBL1065338 | 0.73 | FGFR1 (0.35) | LMNATHRBMTORMDM2NCOA1 | |
| Iodide SCHEMBL29172953 | 0.72 | PIK3CB (0.40) | LMNATHRBMTORMDM2NCOA1 | |
| Hydrochloric Acid SCHEMBL6853659 | 0.72 | PIK3CB (0.40) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL22782146 | 0.72 | LMNA (0.36) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL25378286 | 0.71 | — | — | |
| SCHEMBL22016090 | 0.71 | — | — | |
| SCHEMBL11894064 | 0.71 | — | — | |
| SCHEMBL26050223 | 0.71 | LMNA (0.33) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380877-A | Preparation method of 2' -deoxy-2 ' -beta-fluoro-4 ' -azidocytidine | 和德化学(苏州)有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-112979723-B | Gemcitabine intermediate purification method | 江苏科本药业有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-112979724-B | Mother liquor recovery method of gemcitabine intermediate | 浙江外国语学院 | 2022-04-22 | — | — | CN | disclosed |
| CN-114380877-A | Preparation method of 2' -deoxy-2 ' -beta-fluoro-4 ' -azidocytidine | 和德化学(苏州)有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-112979724-A | Mother liquor recovery method of gemcitabine intermediate | 浙江外国语学院 | 2021-06-18 | — | — | CN | disclosed |
| CN-112979723-A | Gemcitabine intermediate purification method | 江苏科本药业有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-110483413-A | The method for being used to prepare carbocyclic ring sugar derivatives | REXAHN PHARMACEUTICALS INC | 2019-11-22 | — | — | CN | disclosed |
| CN-107474034-A | Method for preparing carbocyclic ring sugar derivatives | 瑞沙恩医药公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-105143191-B | Process for the preparation of 4-amino-1- ((1S, 4R, 5S) -2-fluoro-4, 5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl) -1H-pyrimidin-2-one | 瑞沙恩医药公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-105143191-A | Process for the preparation of 4-amino-1- ((1S, 4R, 5S) -2-fluoro-4, 5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl) -1H-pyrimidin-2-one | REXAHN PHARMACEUTICALS INC | 2015-12-09 | — | — | CN | disclosed |
| WO-2014160799-A1 | AN AUTOMATED, MULTI-POT HIGH-PRESSURE RADIO-SYNTHESIZER FOR PRODUCTION OF PET TRACERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-10-02 | — | — | WO | disclosed |
| US-6034087-A | VIRICIDE AGAINST HEPATITIS B | CHONG KUN DANG CORP. (KR) | 2000-03-07 | — | — | US | disclosed |
| EP-0350293-A2 | Process for preparing derivatives of 2'-deoxy-beta-cytidine and salts thereof | Japan Tobacco Inc. (JP) | 1990-01-10 | — | — | EP | disclosed |