SCHEMBL8080261

SCHEMBL8080261

CC(CCCOc1ccc2cc(C(=O)O)ccc2c1)COc1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.52
KDM4E B2RXH2 1/20 0.51
MAPK1 P28482 1/20 0.51
PLA2G4B P0C869 2/20 0.50
GRIN2D O15399 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49
GRIN2C Q14957 1/20 0.49
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
THRA P10827 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8084886 0.93 MAPK1 (0.56) RARBKDM4EMAPK1PLA2G4BGRIN2D
SCHEMBL8086481 0.91 PLA2G4B (0.52) RARBKDM4EPLA2G4BGRIN2DGRIN2A
SCHEMBL8072285 0.90 MAPK1 (0.56) RARBKDM4EMAPK1PLA2G4BGRIN2D
SCHEMBL8072669 0.90 PLA2G4B (0.54) RARBKDM4EPLA2G4BTP53TSHR
SCHEMBL9779250 0.89 RARB (0.52) RARBKDM4EMAPK1PLA2G4BGRIN2D
SCHEMBL8080346 0.88 KDM4E (0.53) KDM4EMAPK1PLA2G4BGRIN2DGRIN2A
SCHEMBL7289213 0.87 RARB (0.68) RARBKDM4EMAPK1PLA2G4BGRIN2D
SCHEMBL8086354 0.87 MAPK1 (0.67) RARBMAPK1PLA2G4BTP53TSHR
SCHEMBL9779552 0.85 KDM4E (0.55) KDM4EPLA2G4BGRIN2DGRIN2AGRIN2B
SCHEMBL8086815 0.85 KDM4E (0.55) KDM4EPLA2G4BGRIN2DGRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed