SCHEMBL8084886

SCHEMBL8084886

CC(CCOc1ccc2cc(C(=O)O)ccc2c1)COc1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.56
KDM4E B2RXH2 1/20 0.53
RARB P10826 1/20 0.50
PLA2G4B P0C869 1/20 0.48
NR1H4 Q96RI1 2/20 0.47
GRIN2D O15399 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080261 0.93 RARB (0.52) MAPK1KDM4ERARBPLA2G4BGRIN2D
SCHEMBL8080346 0.89 KDM4E (0.53) MAPK1KDM4EPLA2G4BGRIN2DGRIN2A
SCHEMBL8072285 0.89 MAPK1 (0.56) MAPK1KDM4ERARBPLA2G4BNR1H4
SCHEMBL8432107 0.87 MAPK1 (0.73) MAPK1RARBPLA2G4BNR1H4TP53
SCHEMBL8081094 0.87 MAPK1 (0.73) MAPK1RARBPLA2G4BNR1H4TP53
SCHEMBL8086481 0.86 PLA2G4B (0.52) KDM4ERARBPLA2G4BGRIN2DGRIN2A
SCHEMBL9779552 0.86 KDM4E (0.55) KDM4EPLA2G4BNR1H4GRIN2DGRIN2A
SCHEMBL8086815 0.86 KDM4E (0.55) KDM4EPLA2G4BNR1H4GRIN2DGRIN2A
SCHEMBL7278712 0.85 RARB (0.60) MAPK1KDM4ERARBNR1H4GRIN2D
SCHEMBL8072669 0.85 PLA2G4B (0.54) KDM4ERARBPLA2G4BTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed