Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112775 | 0.81 | PIK3CA (0.48) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL2370982 | 0.80 | RAB9A (0.53) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL112798 | 0.79 | RAB9A (0.49) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL15673444 | 0.76 | RAB9A (0.48) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL29470520 | 0.76 | LCK (0.54) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL8739182 | 0.76 | LCK (0.54) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL29470475 | 0.76 | RAB9A (0.48) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL2369646 | 0.75 | RAB9A (0.49) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL144366 | 0.74 | ITK (0.52) | LCKRAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL144365 | 0.74 | ITK (0.52) | LCKRAB9ANPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |