Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087939 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL8080579 | 0.76 | GAA (0.43) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28177430 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL6634972 | 0.71 | KDM4E (0.54) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL7943830 | 0.70 | PARP1 (0.44) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL19667897 | 0.70 | CYP4F2 (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11659717 | 0.69 | POLB (0.45) | HPGDHSD17B10PREPCELA1POLB | |
| SCHEMBL28540877 | 0.68 | CYP4F2 (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL19047101 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL8515697 | 0.68 | BACE1 (0.57) | KDM4EALDH1A1HPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | disclosed |