Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | WEE1 | P30291 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080599 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6634972 | 0.69 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL19667897 | 0.68 | CYP4F2 (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10914392 | 0.67 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8094145 | 0.66 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5464774 | 0.65 | MEN1 (0.54) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL28839422 | 0.63 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6157005 | 0.63 | RAB9A (0.53) | KDM4EALDH1A1HPGDHSD17B10CHEK1 | |
| SCHEMBL6562742 | 0.62 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5171611 | 0.62 | PARP1 (0.46) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | disclosed |