⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957711 | 0.79 | — | — | |
| SCHEMBL8988198 | 0.78 | PDPK1 (0.59) | — | |
| SCHEMBL8080732 | 0.77 | — | — | |
| SCHEMBL13304646 | 0.77 | — | — | |
| SCHEMBL2155849 | 0.77 | — | — | |
| SCHEMBL2373646 | 0.77 | PDPK1 (0.63) | — | |
| SCHEMBL13162008 | 0.76 | — | — | |
| SCHEMBL15651802 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL18209988 | 0.76 | PDPK1 (0.96) | — | |
| SCHEMBL19915187 | 0.75 | PDPK1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106344232-B | Sustained-release drug stent for nasal cavity and forming method and application thereof | 浦易(上海)生物技术股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-0565351-B1 | Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters | LILLY CO ELI (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0494118-B1 | Process for 3-exomethylenecepham sulfoxide esters | LILLY CO ELI (US) | 1997-04-09 | — | — | EP | disclosed |
| US-5512454-A | Enzymatic acylation of 3-hydroxymethyl cephalosporins | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0667396-A1 | Enzymatic acylation of 3-hydroxymethyl cephalosporins | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-08-16 | — | — | EP | disclosed |
| US-5350845-A | Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters | ELI LILLY AND COMPANY (US) | 1994-09-27 | — | — | US | disclosed |
| EP-0611770-A2 | A process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0565351-A2 | Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters | ELI LILLY AND COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| US-5221739-A | Acetylation of 3-hydroxymethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5084568-A | Process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5084447-A | Antibiotics as bactericides | ELI LILLY AND COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5013854-A | Process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0381451-A1 | A process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1990-08-08 | — | — | EP | disclosed |
| EP-0054432-B1 | USE OF 2-BETA-D-RIBOFURANOSYLTHIAZOLE-4-CARBOXAMIDES FOR THE MANUFACTURE OF MEDICAMENTS INHIBITING MALIGNANT TUMORS | VIRATEK, INC. (US) | 1990-01-31 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4885291-A | 1-carba(dethia)-3-cephem derivatives | ELI LILLY AND COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0324562-A1 | 1-Carba(dethia)-3-cephem derivatives | ELI LILLY AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |