Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | MST1R | Q04912 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373646 | 0.87 | PDPK1 (0.63) | PDPK1PLK4CHEK1AURKADAPK3 | |
| SCHEMBL5134164 | 0.85 | IL1B (0.45) | PDPK1TSHRIL1BTDP1MEN1 | |
| SCHEMBL8080735 | 0.78 | — | — | |
| SCHEMBL13162008 | 0.77 | — | — | |
| SCHEMBL28222867 | 0.76 | — | — | |
| SCHEMBL358337 | 0.74 | — | — | |
| SCHEMBL2155849 | 0.74 | — | — | |
| SCHEMBL18927481 | 0.73 | PDPK1 (0.47) | PDPK1PLK4CHEK1AURKADAPK3 | |
| Hydrochloric Acid SCHEMBL18209988 | 0.72 | PDPK1 (0.96) | PDPK1PLK4CHEK1AURKADAPK3 | |
| SCHEMBL15651802 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8081444-A | — | — | None | — | — | JP | disclosed |
| JP-H0881444-A | PYRAZOLE-5-CARBOXAMIDE-4-CARBOXYLIC ACID DERIVATIVE, ITS PRODUCTION, AND AGRICULTURAL/HORTICLTURAL GERMICIDE | UBE IND LTD | 1996-03-26 | — | — | JP | disclosed |
| CN-1015983-B | Process for preparing gametocides pyrazoles | LILLY CO ELI (US) | 1992-03-25 | — | — | CN | disclosed |
| US-4966623-A | POLLEN INHIBITION | ACKMANN STEPHEN A (US) | 1990-10-30 | — | — | US | disclosed |
| US-4902808-A | HYBRID, POLLEN FORMATION INHIBITOR | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0177242-B1 | POLLEN FORMATION INHIBITING PYRAZOLES | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4801326-A | PRODUCTION OF HYBRID SEED | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4775409-A | PREVENTING POLLEN FORMATION | ELI LILLY AND COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0244075-A1 | Gametocidal pyrazoles | ELI LILLY AND COMPANY (US) | 1987-11-04 | — | — | EP | disclosed |
| CN-87102443-A | Cametocidal pyrazoles | — | 1987-10-14 | — | — | CN | disclosed |
| US-4666504-A | HYBRIDS | ELI LILLY AND COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| CN-85107078-A | The pollen that contains pyridine derivate generates composite inhibiting | — | 1987-04-01 | — | — | CN | disclosed |
| EP-0177242-A2 | Pollen formation inhibiting pyrazoles | ELI LILLY AND COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |