Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841715 | 0.86 | DPP7 (0.45) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL7974902 | 0.86 | DPP7 (0.44) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL14090886 | 0.86 | DPP7 (0.44) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL12643957 | 0.86 | KDM4E (0.48) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL27900093 | 0.86 | KDM4E (0.48) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL594596 | 0.86 | KDM4E (0.48) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL7911960 | 0.84 | DPP7 (0.42) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| Hydrochloric Acid SCHEMBL28854822 | 0.84 | KDM4E (0.47) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| Hydrochloric Acid SCHEMBL28854821 | 0.84 | KDM4E (0.47) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL2717436 | 0.83 | DPP7 (0.41) | GNAI3GNAO1GNAI1DPP7RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143790-A | ENZYME INHIBITORS | G.D. SEARLE & CO. (US) | 2000-11-07 | — | — | US | disclosed |
| EP-0749418-B1 | L-N6 -(1-IMINOETHYL)LYSINE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1995024382-A1 | L-N6-(1-IMINOETHYL)LYSINE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-09-14 | — | — | WO | disclosed |