Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14090886 | 1.00 | DPP7 (0.44) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL12619397 | 0.95 | DPP7 (0.41) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL7911960 | 0.89 | DPP7 (0.42) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL2717436 | 0.87 | DPP7 (0.41) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL4094683 | 0.87 | NPY4R (0.44) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL941102 | 0.87 | NPY4R (0.44) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL593995 | 0.86 | KDM4E (0.52) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL27758729 | 0.86 | KDM4E (0.52) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL8080773 | 0.86 | GNAI3 (0.46) | DPP7GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL8082176 | 0.85 | DPP7 (0.42) | DPP7GNAI3GNAO1GNAI1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |