Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 11/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651428 | 0.79 | ALOX5 (0.50) | ALOX5MAOBADORA3GPR84MAOA | |
| SCHEMBL8081262 | 0.75 | ALOX5 (0.62) | ALOX5MAOBADORA3GPR84MAOA | |
| SCHEMBL31634574 | 0.75 | SMN1; SMN2 (0.41) | ALOX5MAOBADORA3GPR84MAOA | |
| SCHEMBL30817881 | 0.74 | ALOX5 (0.56) | ALOX5MAOBGPR84KDM4EALDH1A1 | |
| SCHEMBL1270411 | 0.74 | ALOX5 (0.56) | ALOX5MAOBGPR84KDM4EALDH1A1 | |
| SCHEMBL9080061 | 0.71 | TYMS (0.46) | MAOBMAOAALDH1A1HPGDHSD17B10 | |
| SCHEMBL15024633 | 0.71 | ALOX5 (0.39) | ALOX5MAOBGPR84MAOAKDM4E | |
| SCHEMBL15024628 | 0.69 | MAOB (0.47) | ALOX5MAOBADORA3GPR84MAOA | |
| SCHEMBL10603083 | 0.68 | CYP2A6 (0.50) | MAOAKDM4EALDH1A1TP53MAPT | |
| SCHEMBL15024463 | 0.67 | CYP1A2 (0.40) | ALOX5MAOBGPR84MAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030967-A | AND/OR LIKE NEUROTROPHIC FACTOR (FOR EXAMPLE, NERVE GROWTH FACTOR (NGF), BRAIN-DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-3, AND GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR)-LIKE ACTIVITY; OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-29 | — | — | US | disclosed |