Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL472907 | 0.89 | PTGS1 (0.59) | PTGS1SLC7A11SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL2336576 | 0.84 | DDAH1 (0.47) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL9903954 | 0.84 | DDAH1 (0.47) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL1158189 | 0.84 | DDAH1 (0.47) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Cysteine SCHEMBL28766133 | 0.83 | PTGS1 (0.73) | PTGS1SLC7A11SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL17789224 | 0.82 | SLC1A2 (0.44) | PTGS1SLC7A11SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL1158176 | 0.82 | SLC1A2 (0.44) | PTGS1SLC7A11SLC1A2SLC1A1SLC1A3 | |
| Cysteine SCHEMBL8082573 | 0.82 | PTGS1 (0.64) | PTGS1SLC7A11SLC1A2SLC1A1SLC1A3 | |
| Dodecane SCHEMBL18426078 | 0.81 | PTGS1 (0.70) | PTGS1SLC7A11SLC1A2SLC1A1SLC1A3 | |
| Dodecane SCHEMBL18426080 | 0.81 | PTGS1 (0.70) | PTGS1SLC7A11SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705603-B1 | Use of non-toxic cysteine sulfoxide derivatives in the treatment of cancer | HOLT JOHN ALFRED GORTON (AU) | 2000-08-16 | — | — | EP | disclosed |
| EP-0824919-A2 | Therapeutic methods and compositions for use therein | Holt, John Alfred Gorton (AU) | 1998-02-25 | — | — | EP | disclosed |
| EP-0764442-A1 | Use of specific sulphur containing aminos acid derivatives against pathogenic viral or prion particles | Holt, John Alfred Gorton (AU) | 1997-03-26 | — | — | EP | disclosed |
| EP-0705603-A1 | Use of non-toxic cysteine sulfoxide derivatives in the treatment of cancer or for enhancing the T-cell count | Holt, John Alfred Gorton (AU) | 1996-04-10 | — | — | EP | disclosed |