Glycerin

Glycerin

SCHEMBL8080917

OCC(O)CO.OCC(O)CO.OCC(O)CO.OCC(O)CO.OCC(O)CO.OCC(O)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
ALDH1A1 P00352 1/20 1.00
THRB P10828 1/20 0.57
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.43
MAPT P10636 1/20 0.40
ATM Q13315 1/20 0.40
TSHR P16473 1/20 0.39
OR51E2 Q9H255 1/20 0.35
AKR1B1 P15121 1/20 0.35
USP2 O75604 2/20 0.32
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CSNK2A1 P68400 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL29907853 1.00
Glycerin SCHEMBL3418854 1.00 LMNA (1.00) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL6753203 1.00 LMNA (1.00) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL797 1.00
Glycerin SCHEMBL14278795 1.00
Glycerin SCHEMBL5610362 1.00 LMNA (1.00) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL9439059 1.00 LMNA (1.00) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL14278797 1.00
Glycerin SCHEMBL10453101 1.00 LMNA (1.00) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL29500430 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2997037-A2 COMPOSITION AND METHODS FOR ENTRAPPING A PROTEIN ON A SURFACE Genomics Usa, Inc. (US) 2016-03-23 EP disclosed
WO-2014185960-A9 COMPOSITION AND METHODS FOR ENTRAPPING A PROTEIN ON A SURFACE GENOMICS USA, INC. (US) 2015-03-05 WO disclosed
WO-2014185960-A2 COMPOSITION AND METHODS FOR ENTRAPPING A PROTEIN ON A SURFACE GENOMICS USA, INC. (US) 2014-11-20 WO disclosed
US-6074683-A REACTING A 2-HYDROXYALKYL-SUBSTITUTED 4-HYDROXY-3(2H)-FURANONE WITH H2S AND/OR CYSTEINE LIPTON, INC. (US) 2000-06-13 US disclosed
US-4353958-A POLYURETHANE BINDER NARUMI CHINA CORPORATION (JP) 1982-10-12 US disclosed