Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 17/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070214 | 0.90 | MTOR (0.54) | MTORPIK3CAUSP2 | |
| SCHEMBL15133597 | 0.89 | PIK3CA (0.46) | MTORPIK3CA | |
| SCHEMBL808274 | 0.87 | PIK3CA (0.44) | MTORPIK3CAUSP2 | |
| SCHEMBL808273 | 0.87 | MTOR (0.53) | MTORPIK3CA | |
| SCHEMBL15123601 | 0.86 | PIK3CA (0.46) | MTORPIK3CA | |
| SCHEMBL10070215 | 0.85 | MTOR (0.54) | MTORPIK3CA | |
| SCHEMBL15133594 | 0.84 | MAP3K12 (0.52) | MTORPIK3CA | |
| SCHEMBL10070235 | 0.83 | PIK3CA (0.44) | MTORPIK3CA | |
| SCHEMBL10070217 | 0.83 | PIK3CA (0.55) | MTORPIK3CA | |
| SCHEMBL808275 | 0.83 | PIK3CA (0.55) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012034526-A1 | FUSED HETEROARYLS AND THEIR USES | HUTCHISON MEDIPHARMA LIMITED (CN) | 2012-03-22 | — | — | WO | disclosed |