Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 13/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 12/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 4/20 | 0.39 |
| ▸ | AKT2 | P31751 | 3/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.37 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2519029 | 0.90 | LPAR3 (0.72) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL10773792 | 0.90 | LPAR3 (0.72) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL6854208 | 0.87 | LPAR3 (0.76) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL2224897 | 0.85 | LPAR3 (0.78) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| Pyrophosphoric Acid SCHEMBL8080994 | 0.85 | LPAR3 (0.50) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL26642971 | 0.82 | P2RY10 (0.57) | LPAR3LPAR1 | |
| SCHEMBL22778183 | 0.81 | LPAR1 (0.45) | LPAR3LPAR1LPAR2PLA2G2CAKT1 | |
| SCHEMBL22778250 | 0.79 | LPAR1 (0.43) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| SCHEMBL4565926 | 0.78 | LPAR1 (0.51) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL24470522 | 0.76 | LPAR1 (0.54) | LPAR3LPAR1LPAR2LPAR5LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350287-B1 | Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use | CHIMERIX INC (US) | 2000-09-27 | — | — | EP | disclosed |