Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.39 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566245 | 0.89 | CNR1 (0.51) | LPAR3LPAR1CNR1CNR2ALDH1A1 | |
| SCHEMBL2524076 | 0.89 | CNR1 (0.51) | LPAR3LPAR1CNR1CNR2ALDH1A1 | |
| Pyrophosphoric Acid SCHEMBL15661576 | 0.86 | LPAR3 (0.66) | LPAR3LPAR1CNR1CNR2ALDH1A1 | |
| SCHEMBL8080988 | 0.85 | LPAR3 (0.58) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL2519029 | 0.84 | LPAR3 (0.72) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL10773792 | 0.84 | LPAR3 (0.72) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL3261983 | 0.77 | LPAR3 (0.74) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL1534300 | 0.77 | LPAR3 (0.74) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL7784745 | 0.77 | USP2 (0.50) | LPAR3LPAR1CNR1CNR2ALDH1A1 | |
| Phosphoric Acid SCHEMBL9136512 | 0.77 | LPAR1 (0.69) | LPAR3LPAR1CNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350287-B1 | Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use | CHIMERIX INC (US) | 2000-09-27 | — | — | EP | disclosed |