Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755810 | 0.90 | PREP (0.34) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8083242 | 0.88 | MGLL (0.34) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3738692 | 0.88 | MGLL (0.34) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3736510 | 0.85 | MGLL (0.39) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3738226 | 0.85 | MGLL (0.39) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3748577 | 0.84 | MGLL (0.38) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3744329 | 0.81 | DPP4 (0.38) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13078895 | 0.81 | DPP4 (0.38) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3744735 | 0.80 | DPP4 (0.42) | — | |
| SCHEMBL7859357 | 0.78 | ELANE (0.34) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |