Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465791 | 1.00 | KDM4E (0.53) | KDM4EHIF1ATDP1SLC28A3SLC5A1 | |
| SCHEMBL30852266 | 0.78 | SLC28A3 (0.51) | KDM4EHIF1ATDP1SLC28A3SLC5A1 | |
| SCHEMBL2179543 | 0.78 | SLC28A3 (0.51) | KDM4EHIF1ATDP1SLC28A3SLC5A1 | |
| SCHEMBL30852439 | 0.78 | SLC28A3 (0.51) | KDM4EHIF1ATDP1SLC28A3SLC5A1 | |
| SCHEMBL2423068 | 0.75 | SLC5A1 (0.41) | KDM4ESLC28A3SLC5A1SLC5A2SYNJ2 | |
| SCHEMBL29934345 | 0.71 | KDM4E (1.00) | KDM4EHIF1ATDP1ALPIRECQL | |
| SCHEMBL134058 | 0.71 | KDM4E (1.00) | KDM4EHIF1ATDP1ALPIRECQL | |
| SCHEMBL180582 | 0.71 | KDM4E (1.00) | KDM4EHIF1ATDP1ALPIRECQL | |
| SCHEMBL29375641 | 0.71 | KDM4E (1.00) | KDM4EHIF1ATDP1ALPIRECQL | |
| SCHEMBL29352838 | 0.71 | KDM4E (1.00) | KDM4EHIF1ATDP1ALPIRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038516-A1 | Cosmetic composition comprising kynurenine | Uchikuga, Saburoh (JP) | 2000-09-27 | — | — | EP | disclosed |