Phenylalanine

Phenylalanine

SCHEMBL8081643

C[C@H](NC1CCCCC1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.56
ALPI P09923 1/20 0.56
PKM P14618 1/20 0.56
PTGS1 P23219 1/20 0.56
XIAP P98170 1/20 0.56
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
RECQL P46063 1/20 0.48
KMT2A Q03164 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ANPEP P15144 2/20 0.47
ERAP2 Q6P179 2/20 0.47
KDM4E B2RXH2 1/20 0.46
EPHX2 P34913 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL608840 0.90 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL608841 0.90 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10724525 0.87 ALPI (0.42) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL10724517 0.87 ALPI (0.42) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL3649167 0.86 TPH1 (0.42) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL9318542 0.85 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL9318540 0.85 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL10800577 0.84 ALPI (0.40) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10800585 0.84 ALPI (0.40) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL25221060 0.80 SLC7A5 (0.88) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051388-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO ALCOHOLS BAYER AG (DE) 2000-11-15 EP disclosed
WO-1999038838-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO ALCOHOLS BAYER AKTIENGESELLSCHAFT (DE) 1999-08-05 WO disclosed