Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831416 | 0.86 | MAPT (0.43) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL830689 | 0.81 | MAPT (0.44) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL831311 | 0.79 | MAPT (0.43) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL830293 | 0.75 | ADORA3 (0.41) | MAPTSMN1; SMN2RAB9AADORA3ALDH1A1 | |
| SCHEMBL19895143 | 0.75 | SMN1; SMN2 (0.68) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL831048 | 0.72 | FABP3 (0.46) | MAPTSMN1; SMN2ADORA3CTRCALDH1A1 | |
| SCHEMBL839964 | 0.71 | FABP3 (0.49) | SMN1; SMN2NPC1RAB9AADORA3CTRC | |
| SCHEMBL8024870 | 0.70 | GCGR (0.44) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL831113 | 0.70 | FABP3 (0.48) | SMN1; SMN2NPC1RAB9AADORA3CTRC | |
| SCHEMBL8032664 | 0.70 | CNR2 (0.42) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009033561-A1 | SUBSTITUTED 6-PHEYLNICOTINIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-03-19 | — | — | WO | disclosed |