SCHEMBL80818

SCHEMBL80818

C=CC(=O)OCCC[Si](C)(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.57
ALDH1A1 P00352 4/20 0.57
CYP3A4 P08684 2/20 0.57
HPGD P15428 1/20 0.56
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 2/20 0.40
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL28626350 0.98 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL219314 0.95 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6151224 0.95 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5079807 0.94 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25277799 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286522 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537403 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21402789 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29964436 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29737741 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6993 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080612-A Acrylic acid in-situ polymerized silane modified polyether hybrid resin, application, waterproof coating and preparation method 2026-05-26 CN claimed
US-12629657-B2 Lithium ion adsorbents EMPOWER INNOVATION & TECHNOLOGY LLC (US) 2026-05-19 US claimed
CN-119797809-B Composite water reducer for lithium slag concrete, preparation method and application thereof 中建西部建设新材料科技有限公司 2026-05-15 CN claimed
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition DENKA COMPANY LIMITED (JP) 2026-05-12 US claimed
EP-4735538-A1 1K COATING COMPOSITION AND COATED ARTICLE Sherwin-Williams (Guangdong) New Material Co., Ltd. (CN) 2026-05-06 EP claimed
EP-4652144-A1 PHOTOCURABLE SOL-GEL COMPOSITIONS D. Swarovski KG (AT) 2025-11-26 EP claimed
US-12469872-B2 Fluoropolymer hybrid composite SYENSQO SA (BE) 2025-11-11 US claimed
EP-4615930-A1 HIGH-PERFORMANCE MORTAR COMPRISING TBX AND ANALOGUES fischerwerke GmbH & Co. KG (DE) 2025-09-17 EP claimed
US-12391819-B2 Fluoropolymer-based hybrid organic/inorganic composites SYENSQO SA (BE) 2025-08-19 US claimed
EP-3724939-B1 FLUOROPOLYMER MEMBRANE FOR ELECTROCHEMICAL DEVICES SYENSQO SA (BE) 2025-08-13 EP claimed
US-5449716-A Curable composition of silane and polysiloxanes with catalyst DOW CORNING CORPORATION (US) 1995-09-12 US claimed
EP-0665252-A2 Two-pack aqueous coating composition KANSAI PAINT CO., LTD. (JP) 1995-08-02 EP claimed
EP-0659817-A1 Acrylic rubber-based composition NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 1995-06-28 EP claimed
EP-0358153-B1 Automotive coating compositions KANSAI PAINT CO LTD (JP) 1994-01-12 EP claimed
US-5051473-A An acrylic monomer containing a siloxane group and a polysiloxane polymer, a chelate compound and a compound with two oxirane groups KANSAI PAINT COMPANY, LIMITED (JP) 1991-09-24 US claimed
US-4988788-A Room temperature-curable coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-01-29 US claimed
EP-0358153-A2 Automotive coating compositions KANSAI PAINT CO., LTD. (JP) 1990-03-14 EP claimed
US-4886852-A PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION KANSAI PAINT COMPANY, LIMITED (JP) 1989-12-12 US claimed
EP-0268243-A2 Packing material and process for its production Tosoh Corporation (JP) 1988-05-25 EP claimed
US-4543403-A .MOISTURE CURABLE SILANE ENDCAPPED ACRYLIC POLYMER, TELECHELIC KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-09-24 US claimed