Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80818 | 0.94 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Ethylene SCHEMBL28626350 | 0.92 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL71730 | 0.92 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Methane SCHEMBL28113061 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28323519 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Ethylene SCHEMBL22126280 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28208777 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL441818 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL21670464 | 0.89 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL219314 | 0.89 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1273601-B1 | RUBBER-MODIFIED RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME | KANEKA CORP (JP) | 2008-02-27 | — | — | EP | disclosed |
| EP-1160290-B1 | FLAME RETARDANT FOR THERMOPLASTIC RESIN AND FLAME-RETARDANT RESIN COMPOSITION | KANEKA CORP (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6822045-B2 | MIXTURE OF ACRYLIC POLYMER AND SILICONE RUBBER | KANEKA CORPORATION (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20030092819-A1 | Rubber-modified resin and thermoplastic resin composition containing the same | KANEKA CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1273601-A1 | RUBBER-MODIFIED RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME | KANEKA CORPORATION (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-1160290-A1 | FLAME RETARDANT FOR THERMOPLASTIC RESIN AND FLAME-RETARDANT RESIN COMPOSITION | KANEKA CORPORATION (JP) | 2001-12-05 | — | — | EP | disclosed |