Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452742 | 0.90 | GAA (0.55) | MAPTGAAALDH1A1HTTMEN1 | |
| SCHEMBL8078834 | 0.81 | MAPT (0.56) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL8077130 | 0.79 | HIF1A (0.46) | MAPTGAAALDH1A1HTTMEN1 | |
| SCHEMBL11463349 | 0.78 | GAA (0.55) | MAPTGAAALDH1A1PTGS2CYP3A4 | |
| SCHEMBL23647529 | 0.77 | IDO1 (0.49) | MAPTGAAALDH1A1HTTMEN1 | |
| SCHEMBL9497275 | 0.76 | HSPB1 (0.59) | MAPTGAAALDH1A1HTTMEN1 | |
| SCHEMBL10643494 | 0.76 | GAA (0.58) | MAPTGAAALDH1A1PTGS2LMNA | |
| SCHEMBL9082994 | 0.76 | HSPB1 (0.59) | MAPTGAAALDH1A1HTTMEN1 | |
| SCHEMBL3045885 | 0.76 | MAPT (0.68) | MAPTGAAALDH1A1MEN1NPC1 | |
| SCHEMBL6671840 | 0.75 | HSD17B10 (0.56) | MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6137008-A | USEFUL AS STARTING MATERIAL FOR MAKING FLEXIBLE AROMATIC POLYAMIDES OR POLYIMIDES | NATIONAL SCIENCE COUNCIL (TW) | 2000-10-24 | — | — | US | disclosed |