SCHEMBL8081852

SCHEMBL8081852

CCCC1CCC(CCOc2ccccc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.50
TEAD1 P28347 1/20 0.50
TEAD3 Q99594 1/20 0.50
NFE2L2 Q16236 1/20 0.47
KCNA3 P22001 1/20 0.47
CHRNB2 P17787 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
CHRNA7 P36544 1/20 0.44
CHRNA4 P43681 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
HRH3 Q9Y5N1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8529857 1.00 LTA4H (0.50) LTA4HTEAD1TEAD3NFE2L2KCNA3
SCHEMBL9346498 0.95 TEAD1 (0.47) LTA4HTEAD1TEAD3NFE2L2KCNA3
SCHEMBL9346506 0.95 TEAD1 (0.47) LTA4HTEAD1TEAD3NFE2L2KCNA3
SCHEMBL9344705 0.91 LTA4H (0.53) LTA4HTEAD1TEAD3KCNA3CHRNB2
SCHEMBL9344709 0.91 LTA4H (0.53) LTA4HTEAD1TEAD3KCNA3CHRNB2
SCHEMBL4980425 0.91 TEAD1 (0.56) TEAD1TEAD3NFE2L2KCNA3TAAR1
SCHEMBL8078945 0.90 KCNA3 (0.53) LTA4HTEAD1TEAD3KCNA3CHRNB2
SCHEMBL8753521 0.90 KCNA3 (0.53) LTA4HTEAD1TEAD3KCNA3CHRNB2
SCHEMBL9349635 0.89 TEAD1 (0.50) LTA4HTEAD1TEAD3NFE2L2KCNA3
SCHEMBL9349642 0.89 TEAD1 (0.50) LTA4HTEAD1TEAD3NFE2L2KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60255806-A None JP disclosed
EP-0805134-B1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORP (JP) 2000-08-30 EP disclosed
US-6086964-A Liquid crystalline compound having dienyl moiety and liquid crystal composition CHISSO CORPORATION (JP) 2000-07-11 US disclosed
US-6001275-A LIQUID CRYSTALLINE COMPOUND WHICH HAS A LARGE RATIO OF ELASTIC CONSTANTS, HAS A LOW VISCOSITY, EXCELLENT MISCIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUND, CHEMICALLY STABLE; HAVING AN UNCONJUGATED ALKADIENYL GROUP AT A SIDE CHAIN. CHISSO CORPORATION (JP) 1999-12-14 US disclosed
EP-0672742-B1 A hexenediyne derivative and a liquid crystal composition CHISSO CORP (JP) 1999-02-10 EP disclosed
EP-0733610-B1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device CHISSO CORP (JP) 1998-10-28 EP disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed
EP-0597701-B1 Conjugated enyne derivative and liquid crystal composition CHISSO CORP (JP) 1997-04-16 EP disclosed
EP-0733610-A1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0672742-A1 A hexenediyne derivative and a liquid crystal composition CHISSO CORPORATION (JP) 1995-09-20 EP disclosed
EP-0432780-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAID COMPOSITION CHISSO CORPORATION (JP) 1993-07-21 EP disclosed
EP-0364588-B1 LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1993-02-10 EP disclosed
US-5102577-A Supertwisted birefringence system CHISSO CORPORATION (JP) 1992-04-07 US disclosed
EP-0432780-A1 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1991-06-19 EP disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 EP disclosed
US-4935160-A Liquid-crystal guest-host systems MERCK PATENT GESSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-06-19 US disclosed
EP-0364588-A1 LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1990-04-25 EP disclosed
EP-0318003-A2 A liquid crystal composition for twist nematic mode CHISSO CORPORATION (JP) 1989-05-31 EP disclosed
EP-0316186-A2 Liquid crystal compositions Chisso Corporation (JP) 1989-05-17 EP disclosed
JP-S60255806-A PRODUCTION OF ACETYLENE POLYMER HITACHI LTD 1985-12-17 JP disclosed