Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075562 | 1.00 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8077450 | 1.00 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8077202 | 1.00 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8067502 | 1.00 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8081952 | 1.00 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8080501 | 1.00 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8082110 | 1.00 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8082081 | 0.99 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8082020 | 0.97 | XDH (0.41) | XDHPTGER1ALKBH1MRGPRX4THRB | |
| SCHEMBL8082135 | 0.91 | HDAC1 (0.44) | PTGER1MRGPRX4THRBHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755918-B1 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | ROLIC AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| US-5800733-A | Photo cross-linkable liquid crystal derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |
| EP-0755918-A2 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | Rolic AG (CH) | 1997-01-29 | — | — | EP | disclosed |