Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714298 | 0.86 | POLB (0.75) | POLBCYP3A4CYP2C9ABCB1 | |
| Rh-5849 SCHEMBL1538531 | 0.84 | POLB (1.00) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9714363 | 0.82 | CYP3A4 (0.81) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL4150390 | 0.82 | POLB (0.82) | POLBCYP3A4CYP2C9 | |
| SCHEMBL8175233 | 0.82 | ABCB1 (0.82) | POLBCYP3A4CYP2C9ABCB1 | |
| Halofenozide SCHEMBL55120 | 0.82 | POLB (0.82) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9342048 | 0.81 | CYP3A4 (0.74) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9714296 | 0.81 | POLB (0.75) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL10720371 | 0.81 | POLB (0.75) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL10720015 | 0.80 | CYP3A4 (0.76) | POLBCYP3A4CYP2C9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000026423-A | ISONICOTINOYLHYDRAZINE DERIVATIVE AND INSECT PEST CONTROLLING AGENT CONTAINING THE SAME DERIVATIVE AS ACTIVE INGREDIENT | OTSUKA CHEM CO LTD | 2000-01-25 | — | — | JP | disclosed |