SCHEMBL808215

SCHEMBL808215

Cc1nc(N2CCC(C)(c3cc(Cl)c(Cl)c(Cl)c3)C2)ccc1CNC(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 7/20 0.36
KLKB1 P03952 3/20 0.36
SUV39H2 Q9H5I1 4/20 0.35
IDO1 P14902 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PTGES O14684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10279687 0.87 EPHX2 (0.37) DRD2KLKB1SUV39H2IDO1TRPV1
SCHEMBL808210 0.78 PTPN11 (0.34) KLKB1
SCHEMBL12467010 0.76 EPHX2 (0.40) KLKB1TRPV1PTGES
SCHEMBL794543 0.74 EPHX2 (0.38) KLKB1TRPV1PTGES
SCHEMBL807797 0.74 PTPN11 (0.34)
SCHEMBL17874869 0.69 EPHX2 (0.39) DRD2TRPV1PTGES
SCHEMBL807621 0.69 CACNA1H (0.40) TRPV1ALDH1A1
SCHEMBL15888063 0.68 TRPV1 (0.37) TRPV1
SCHEMBL15888062 0.67 TRPV1 (0.35) TRPV1
SCHEMBL16814047 0.67 KDM4A (0.44) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012035011-A1 PESTICIDAL ARYLPYRROLIDINES BAYER CROPSCIENCE AG (DE) 2012-03-22 WO disclosed