Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467260 | 0.88 | TACR1 (0.35) | TACR1MCHR1TRPV1OPRM1CYP2D6 | |
| SCHEMBL10279687 | 0.82 | EPHX2 (0.37) | TRPV1 | |
| SCHEMBL799014 | 0.81 | SCD (0.42) | MCHR1CYP2D6TSHRALDH1A1 | |
| SCHEMBL795181 | 0.81 | CACNA1H (0.39) | CACNA1HCACNA1BCACNA1CTACR1CCR2 | |
| SCHEMBL12467053 | 0.80 | CYP3A4 (0.33) | TACR1MCHR1CYP2D6TSHRALDH1A1 | |
| SCHEMBL794384 | 0.80 | TACR1 (0.33) | TACR1MCHR1CYP2D6TSHR | |
| SCHEMBL794132 | 0.80 | SCD (0.35) | MCHR1CYP2D6TSHR | |
| SCHEMBL795686 | 0.79 | NR1H2 (0.34) | TACR1MCHR1TRPV1OPRM1CYP2D6 | |
| SCHEMBL795833 | 0.78 | CYP1A2 (0.34) | MCHR1TRPV1CYP2D6TSHRALDH1A1 | |
| SCHEMBL15474198 | 0.77 | SCD (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | CACNA1H 422/4885CACNA1B 362/4885CACNA1C 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.