⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121913 | 0.81 | — | — | |
| SCHEMBL30792966 | 0.79 | TP53 (0.36) | — | |
| SCHEMBL79921 | 0.74 | — | — | |
| SCHEMBL29720648 | 0.74 | — | — | |
| SCHEMBL29839691 | 0.74 | — | — | |
| SCHEMBL3880085 | 0.74 | — | — | |
| SCHEMBL959207 | 0.74 | — | — | |
| SCHEMBL29443091 | 0.73 | — | — | |
| SCHEMBL530450 | 0.73 | — | — | |
| SCHEMBL17135281 | 0.72 | CES2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591290-A | Preparation method of substituted benzo [ B ] naphthalene benzene [2, 3-D ] thiophene derivative and derivative | 陕西维世诺新材料有限公司 | 2022-06-07 | — | — | CN | claimed |
| US-4870218-A | Trihalobenzene compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-26 | — | — | US | claimed |
| EP-0252592-A1 | Halogenated diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-13 | — | — | EP | claimed |
| EP-4685143-A1 | DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF | Vivozon,Inc. (KR) | 2026-01-28 | — | — | EP | disclosed |
| EP-4638438-A1 | ALPHA4 BETA7 INTEGRIN ANTAGONISTS AND USES THEREOF | Xinthera, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| CN-119176772-A | Compound with Mrgpr X receptor inhibition effect and application thereof | 博济医药科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-118693282-B | Secondary battery and preparation method and application thereof | 蜂巢能源科技股份有限公司 | 2024-12-03 | — | — | CN | disclosed |
| WO-2024196136-A1 | DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF | 주식회사 비보존 | 2024-09-26 | — | — | WO | disclosed |
| CN-118693282-A | Secondary battery and preparation method and application thereof | 蜂巢能源科技股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| US-20240299385-A1 | 3-PYRROLYLSULFONAMIDE COMPOUNDS AS GPR17 ANTAGONISTS | REWIND THERAPEUTICS NV (BE) | 2024-09-12 | — | — | US | disclosed |
| US-20240279214-A1 | ALPHA4 BETA7 INEGRIN ANTAGONISTS AND USES THEREOF | XINTHERA, INC. | 2024-08-22 | — | — | US | disclosed |
| WO-2012143725-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | ASTEX THERAPEUTICS LIMITED (GB) | 2012-10-26 | — | — | WO | disclosed |
| US-8129361-B2 | Amine compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100179216-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-07-15 | — | — | US | disclosed |
| US-7732463-B2 | 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors | H. LUNDBECK A/S (DK) | 2010-06-08 | — | — | US | disclosed |
| EP-2168944-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |
| CN-1780622-A | 4-(2-phenylsulfanyl-phenyl)-piperidine derivates as serotonin reuptake inhibitors | LUNDBECK & CO AS H (DK) | 2006-05-31 | — | — | CN | disclosed |
| US-20060100242-A1 | such as 4-[2-(4-Chloro-phenylsulfanyl)-5-trifluoromethyl-phenyl]-piperidine, used as antidepressants and anxiolytic agents; treatment of panic and obsessive compulsive disorders | H.LUNDBECK A/S (DK) | 2006-05-11 | — | — | US | disclosed |
| EP-1626720-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004087156-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2004-10-14 | — | — | WO | disclosed |