Benzene

Benzene

SCHEMBL8082220

CCCCCCN.c1ccccc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.81
TSHR P16473 3/20 0.81
MEN1 O00255 1/20 0.81
KMT2A Q03164 1/20 0.81
ALDH1A1 P00352 1/20 0.81
EPHX1 P07099 1/20 0.81
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA3 P07451 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 1/20 0.50
BLM P54132 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Decylamine SCHEMBL28794198 1.00 DNM1 (0.81) DNM1TSHRMEN1KMT2AALDH1A1
Octadecylamine SCHEMBL29219558 1.00 DNM1 (0.81) DNM1TSHRMEN1KMT2AALDH1A1
Dodecylamine SCHEMBL2467385 1.00 DNM1 (0.81) DNM1TSHRMEN1KMT2AALDH1A1
Octadecylamine SCHEMBL11865540 0.97 DNM1 (0.82) DNM1TSHRMEN1KMT2AALDH1A1
Dodecylamine SCHEMBL28201901 0.97 DNM1 (0.82) DNM1TSHRMEN1KMT2AALDH1A1
Benzene SCHEMBL11103587 0.97 DNM1 (0.75) DNM1TSHRMEN1KMT2AALDH1A1
Benzene SCHEMBL10436942 0.94 DNM1 (0.77) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL23850566 0.90 DNM1 (1.00) DNM1TSHRMEN1KMT2AALDH1A1
Octadecylamine SCHEMBL8339913 0.90 DNM1 (1.00) DNM1TSHRMEN1KMT2AALDH1A1
Icosylamine SCHEMBL11365935 0.90 DNM1 (1.00) DNM1TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105025710-A Pesticide composition RHODIA OPERATIONS 2015-11-04 CN disclosed
CN-102816107-B Carbazole derivative and preparation method and use thereof UNIV SOUTHEAST 2015-06-03 CN disclosed
CN-102653526-B 2, 3-diaryl thiazolinone compound and usage thereof in preparation of medicine for treating tumour UNIV EAST CHINA NORMAL 2015-04-08 CN disclosed
CN-102786493-B 2,3-diaryl thiazolidinone compound and analogue, and purpose thereof in preparing antiangiogenic drugs EAST CHINA NORMAL UNIVERSITY (CN) 2014-10-01 CN disclosed
CN-102816107-A Carbazole derivative and preparation method and use thereof UNIV SOUTHEAST 2012-12-12 CN disclosed
CN-102786493-A 2,3-diaryl thiazolidinone compound and analogue, and purpose thereof in preparing antiangiogenic drugs UNIV EAST CHINA NORMAL 2012-11-21 CN disclosed
CN-102653526-A 2, 3-diaryl thiazolinone compound and usage thereof in preparation of medicine for treating tumour UNIV EAST CHINA NORMAL 2012-09-05 CN disclosed
CN-1723270-A Grease composition for automobile electrical equipment auxiliary device and prelubricated rolling bearing using the grease composition NSK LTD (JP) 2006-01-18 CN disclosed
EP-0735113-B1 Mixtures of reactive dyes and their use CIBA SC HOLDING AG (CH) 2000-10-18 EP disclosed
US-5892006-A CONTAINING S-TRIAZINE RINGS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-04-06 US disclosed
EP-0458743-A2 Reactive dyestuffs, methods of their preparation and use CIBA-GEIGY AG (CH) 1991-11-27 EP disclosed
US-5021557-A Copper-containing formazan dye, colorfast blue shades on cellulose CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
CN-1012615-B POLYMARIZATION METHOD FOR PRODCING POLYACRYLATES POLYMER TECHNOLOGY INC (US) 1991-05-15 CN disclosed
CN-1040801-A Polymarization method for prodcing polyacrylates POLYMER TECHNOLOGY INC (US) 1990-03-28 CN disclosed
EP-0333656-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1989-09-20 EP disclosed
US-4841049-A FOR CELLULOSIC FIBERS; BRIGHT BLUE COLORS; WET- AND LIGHTFAST CIBA-GEIGY CORPORATION (US) 1989-06-20 US disclosed
EP-0260227-A1 Dioxazine reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1988-03-16 EP disclosed
US-4578457-A Reactive mono-azo dyes and the preparation and use thereof CIBA-GEIGY AG (CH) 1986-03-25 US disclosed
EP-0101665-A2 Reactive dyestuffs of the dioxazine series, their preparation and their use CIBA-GEIGY AG (CH) 1984-02-29 EP disclosed
EP-0073178-A1 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1983-03-02 EP disclosed