SCHEMBL8082282

SCHEMBL8082282

CCCCC(C)COc1ccc(C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 7/20 0.62
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
MAPK1 P28482 1/20 0.56
RARB P10826 5/20 0.56
PLA2G4A P47712 1/20 0.54
NR1H4 Q96RI1 2/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080407 0.96 RARB (0.63) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL8081866 0.95 PLA2G4B (0.64) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL8081722 0.92 RARB (0.66) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL8081903 0.91 MAPK1 (0.59) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL8086354 0.89 MAPK1 (0.67) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL9868849 0.88 TP53 (0.69) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL8086481 0.88 PLA2G4B (0.52) PLA2G4BTP53TSHRRARB
SCHEMBL8084860 0.87 RARB (0.59) PLA2G4BTP53TSHRMAPK1RARB
SCHEMBL12112442 0.85 TSHR (0.56) PLA2G4BTSHR
SCHEMBL9869039 0.85 TP53 (0.75) PLA2G4BTP53TSHRMAPK1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed