Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869705 | 0.91 | CCR5 (0.42) | CCR5 | |
| SCHEMBL7836260 | 0.90 | CCR5 (0.60) | CCR5 | |
| SCHEMBL7838241 | 0.89 | CCR5 (0.50) | CCR5 | |
| SCHEMBL8089197 | 0.85 | CCR5 (0.56) | CCR5 | |
| SCHEMBL7826160 | 0.81 | CCR5 (0.65) | CCR5 | |
| SCHEMBL7837039 | 0.79 | CCR5 (0.79) | CCR5 | |
| SCHEMBL2339218 | 0.79 | CCR5 (0.49) | CCR5 | |
| SCHEMBL14371075 | 0.79 | CCR5 (0.49) | CCR5 | |
| Hydrochloric Acid SCHEMBL2338754 | 0.79 | CCR5 (0.48) | CCR5 | |
| SCHEMBL7870851 | 0.76 | CCR5 (0.46) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166037-A | Pyrrolidine and piperidine modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2000-12-26 | — | — | US | disclosed |