Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646033 | 0.95 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL14519061 | 0.91 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL27552085 | 0.89 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL28479263 | 0.85 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL11903655 | 0.85 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL29277397 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL29071735 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL9317815 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL29277420 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL8702147 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044214-A1 | METHOD FOR BINDING ALBUMIN AND MEANS TO BE USED IN THE METHOD | Amersham Pharmacia Biotech AB (SE) | 2000-10-18 | — | — | EP | disclosed |
| US-5994507-A | CONTACTING AQUEOUS LIQUID CONTAINING ALBUMIN WITH A COMPOUND CONTAINING THE SCAFFOLD--C(=O)-NH-C(=C-)-C(=O)- AND HAVING BEEN PRE-CHECKED TO BIND TO THE ALBUMIN; FOR REMOVAL OF ALBUMIN FROM A SOLUTION OR FOR PURIFICATION OF ALBUMIN | AMERSHAM PHARMACIA BIOTECH AB (SE) | 1999-11-30 | — | — | US | disclosed |
| WO-1999033860-A1 | METHOD FOR BINDING ALBUMIN AND MEANS TO BE USED IN THE METHOD | AMERSHAM PHARMACIA BIOTECH AB (SE) | 1999-07-08 | — | — | WO | disclosed |