SCHEMBL80829

SCHEMBL80829

BrCc1cccc(OCc2ccccc2)c1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.68
BCHE P06276 8/20 0.66
CYP4F2 P78329 1/20 0.64
CYP4A11 Q02928 1/20 0.64
MAOA P21397 1/20 0.57
NR4A2 P43354 1/20 0.57
ALOX5 P09917 1/20 0.56
LCK P06239 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29411728 1.00 MAOB (0.68) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL1775149 0.89 MAOB (0.58) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL4825449 0.86 MEN1 (0.58) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL21429714 0.86 MAOB (0.55) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL4158572 0.86 MAOB (0.69) MAOBBCHEMAOANR4A2
SCHEMBL15761340 0.86 BCHE (0.70) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL1268719 0.86 MAOB (0.81) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL9707070 0.85 FFAR1 (0.59) MAOBBCHECYP4F2CYP4A11LCK
SCHEMBL27733468 0.85 CYP4F2 (0.70) MAOBBCHECYP4F2CYP4A11MAOA
SCHEMBL5027658 0.85 MEN1 (0.56) MAOBBCHECYP4F2CYP4A11MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959962-B Visible light-promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
CN-115850002-B Method for hydrodehalogenating halogenated alkane 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
CN-119101052-A Matrine-triazole derivative and synthesis method thereof 吉林医药学院 2024-12-10 CN claimed
EP-4711355-A1 CRYSTAL FORM OF LIPOPROTEIN COMPOUND AND PREPARATION METHOD THEREFOR Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-03-18 EP disclosed
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD TOPAZ THERAPEUTICS INC (US) 2026-01-22 US disclosed
US-20250388565-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND METHODS OF USE THEREOF RELAY THERAPEUTICS, INC. 2025-12-25 US disclosed
US-12459895-B2 MEK inhibitors and uses thereof Ikena Oncology, Inc. (US) 2025-11-04 US disclosed
US-20250325687-A1 CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST MABSOFT THERAPEUTICS SHANGHAI CO LTD (CN) 2025-10-23 US disclosed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
CN-115959962-B Visible light-promoted halogenated alkane hydrodehalogenation method 中国科学院兰州化学物理研究所 2025-05-23 CN disclosed
CN-115850002-B Method for hydrodehalogenating halogenated alkane 中国科学院兰州化学物理研究所 2025-05-23 CN disclosed
WO-1995000146-A1 AMINO BI- AND TRI-CARBOCYCLIC ALKANE BIS-ARYL SQUALENE SYNTHASE INHIBITORS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1995-01-05 WO disclosed
WO-1994027601-A1 ALIPHATIC AMINO BIS-ARYL SQUALENE SYNTHASE INHIBITORS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1994-12-08 WO disclosed
WO-1992015579-A1 MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHETASE INHIBITORS RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-09-17 WO disclosed
EP-0434365-A2 HIV protease inhibitors useful for the treatment of aids MERCK & CO. INC. (US) 1991-06-26 EP disclosed
US-4347375-A Process for preparing amino acids and esters MERCK & CO., INC. (US) 1982-08-31 US disclosed
EP-0007615-B1 PROCESS FOR PREPARING AMINO ACIDS AND ESTERS MERCK & CO. INC. (US) 1982-06-16 EP disclosed
US-4275220-A N-(BENZYLIDENE OR ALKYLIDENE)-2-AMINOCROTONATE CHEMICAL INTERMEDIATE MERCK & CO., INC. (US) 1981-06-23 US disclosed
EP-0008657-A1 Alpha-vinyl-alpha-aminoacids and their esters and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1980-03-19 EP disclosed
EP-0007615-A2 Process for preparing amino acids and esters MERCK & CO. INC. (US) 1980-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388565-A1 ESTROGEN RECEPTOR ALPHA DEGRADERS AND METHODS OF USE THEREOF ESRRA, ESRRB, ESR2 MAOB 958/4885BCHE 1315/4885CYP4F2 445/4885
US-12459895-B2 MEK inhibitors and uses thereof BRAF, NRAS, KRAS MAOB 3464/4885BCHE 4050/4885CYP4F2 3669/4885
US-20250325687-A1 CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST TLR3, TLR7, TLR8 MAOB 2823/4885BCHE 4269/4885CYP4F2 4594/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 MAOB 604/4885BCHE 2575/4885CYP4F2 1153/4885
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD RIOX2, ORC3, DCLRE1A MAOB 3262/4885BCHE 4304/4885CYP4F2 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.