Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411728 | 0.85 | MAOB (0.68) | MAOBBCHELCKCYP4F2CYP4A11 | |
| SCHEMBL80829 | 0.85 | MAOB (0.68) | MAOBBCHELCKCYP4F2CYP4A11 | |
| SCHEMBL282581 | 0.85 | LMNA (0.64) | FFAR1FFAR4MAOBBCHELMNA | |
| SCHEMBL202774 | 0.85 | ALDH1A1 (0.54) | MAOB | |
| SCHEMBL9491438 | 0.84 | FFAR1 (0.68) | FFAR1FFAR4MAOBBCHELCK | |
| Bromide SCHEMBL11317156 | 0.84 | ALDH1A1 (0.53) | FFAR1FFAR4MAOB | |
| SCHEMBL1437775 | 0.83 | APP (0.64) | FFAR1FFAR4MAOBBCHELMNA | |
| SCHEMBL1775149 | 0.82 | MAOB (0.58) | FFAR1MAOBBCHELCKCYP4F2 | |
| SCHEMBL891493 | 0.82 | FFAR1 (0.69) | FFAR1FFAR4MAOBBCHELMNA | |
| SCHEMBL11849334 | 0.82 | LMNA (0.69) | FFAR1FFAR4MAOBBCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015579-A1 | MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHETASE INHIBITORS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-09-17 | — | — | WO | disclosed |