⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29224793 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL28869458 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL22200070 | 0.70 | — | — | |
| SCHEMBL29224789 | 0.70 | ALDH1A1 (0.40) | — | |
| SCHEMBL8995379 | 0.69 | ALDH1A1 (0.44) | — | |
| SCHEMBL2101357 | 0.69 | — | — | |
| SCHEMBL8995402 | 0.69 | ALDH1A1 (0.44) | — | |
| SCHEMBL29224784 | 0.68 | TSHR (0.40) | — | |
| SCHEMBL1929982 | 0.67 | — | — | |
| SCHEMBL11030371 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633265-B1 | Process for preparation of beta-cyanoalkylsilanes | DOW CORNING (US) | 2000-10-25 | — | — | EP | disclosed |
| EP-0525997-B1 | Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles | DOW CORNING (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5283348-A | Process for preparation of β-cyanoalkylsilanes | DOW CORNING CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0520645-A1 | Process for preparation of beta-cyanoalkylsilanes | DOW CORNING CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5126469-A | Supported catalysts for addition of silicon hydrides to α,β-unsaturated olefinic nitriles | DOW CORNING CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |
| US-5126468-A | Diamine and copper or copper compound | DOW CORNING CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0057459-B1 | PLATINUM-STYRENE COMPLEXES AS CATALYSTS FOR HYDROSILATION REACTIONS AND A PROCESS FOR PREPARING THE SAME | SWS Silicones Corporation (US) | 1985-01-30 | — | — | EP | disclosed |
| US-4450283-A | REACTING PLATINUM HALIDE AND STYRENE COMPOUND IN PRESENCE OF A BASE | SWS SILICONES CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |
| US-4398010-A | CONTAINING PLATINUM | SWS SILICONES CORPORATION (US) | 1983-08-09 | — | — | US | disclosed |
| US-4394317-A | CURING POLYSILOXANES | SWS SILICONES CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0057459-A1 | Platinum-styrene complexes as catalysts for hydrosilation reactions and a process for preparing the same | SWS Silicones Corporation (US) | 1982-08-11 | — | — | EP | disclosed |
| US-4033902-A | USED FOR SILANATION, MADE FROM PLATINUM DICHLORIDE AND COBALT OCTACARBONYL | SWS SILICONES CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |