Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086091 | 1.00 | AGTR1 (0.57) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10536918 | 0.91 | AGTR1 (0.51) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10538106 | 0.90 | AGTR1 (0.57) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10540415 | 0.90 | AGTR1 (0.50) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10541904 | 0.86 | NPC1 (0.61) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10541374 | 0.85 | KDM4E (0.55) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL10540484 | 0.84 | KDM4E (0.54) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL41828 | 0.82 | ABAT (0.53) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL1330698 | 0.82 | ABAT (0.53) | AGTR1RAB9AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3069393 | 0.82 | ABAT (0.53) | AGTR1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038533-A1 | MEDICINAL COMPOSITIONS FOR TREATING IMMUNODEFICIENCY DISEASES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-09-27 | — | — | EP | disclosed |
| EP-0347820-B1 | NOVEL SPERGUALIN-RELATED COMPOUNDS AND PREPARATION AND APPLICATION OF THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-5061787-A | IMMUNOSUPPRESSANTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0241797-B1 | NOVEL SPERGUALIN-RELATED COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4956504-A | IMMUNOMODULATORS, ANTIBIOTICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0309971-A2 | New spergualin-related compound and pharmaceutical composition | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-04-05 | — | — | EP | disclosed |
| EP-0241797-A2 | Novel spergualin-related compounds and process for producing the same | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 1987-10-21 | — | — | EP | disclosed |