SCHEMBL8083109

SCHEMBL8083109

CC(C)C1CCC(C)(O)C(O)(c2ccccc2)C1c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.37
NPSR1 Q6W5P4 3/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
OPRK1 P41145 2/20 0.35
OPRL1 P41146 2/20 0.35
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
CHRNA7 P36544 1/20 0.33
ATM Q13315 2/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
SLC18A3 Q16572 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALDH1A1 P00352 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ABCB1 P08183 1/20 0.31
MAPK1 P28482 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28181546 0.75 ATM (0.35) TRPA1NPSR1MEN1MAPTKMT2A
SCHEMBL8083114 0.74 OPRL1 (0.37) TRPA1NPSR1MEN1MAPTKMT2A
SCHEMBL27847723 0.66 OPRL1 (0.35) OPRK1OPRL1OPRM1OPRD1HTT
SCHEMBL8501660 0.66 SLC18A3 (0.42) TRPA1NPSR1MEN1MAPTKMT2A
SCHEMBL27854099 0.65 OPRL1 (0.44) TRPA1OPRK1OPRL1OPRM1
SCHEMBL27485524 0.63 OPRL1 (0.35) OPRL1
SCHEMBL11755106 0.62 OPRL1 (0.34) OPRK1OPRL1OPRM1
SCHEMBL28855370 0.62 OPRL1 (0.34) OPRK1OPRL1OPRM1
SCHEMBL11437591 0.62 OPRL1 (0.34) OPRL1SLC18A3
SCHEMBL10410682 0.61 GRIN2B (0.34) MAPTOPRL1SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956314-B1 Refuse containers with biocide. OTTO GMBH & CO KG GEB (DE) 2000-10-18 EP disclosed
EP-0956314-A1 POLYMER COMPOSITION, THE PRODUCTION AND FURTHER PROCESSING THEREOF INTO RECEPTACLES Gebr. OTTO KG (DE) 1999-11-17 EP disclosed
WO-1999037710-A1 POLYMER COMPOSITION, THE PRODUCTION AND FURTHER PROCESSING THEREOF INTO RECEPTACLES GEBR. OTTO KG (DE) 1999-07-29 WO disclosed