Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 3/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911019 | 0.86 | ESR2 (0.36) | SLC18A3TRPA1 | |
| SCHEMBL28494433 | 0.85 | SLC18A3 (0.39) | SLC18A3KDM4AKDM4BKDM4CIDO1 | |
| SCHEMBL29266620 | 0.85 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL11437591 | 0.80 | OPRL1 (0.34) | SLC18A3IDO1TDO2OPRL1CCR2 | |
| SCHEMBL12804545 | 0.79 | IDO1 (0.35) | SLC18A3IDO1TDO2OPRL1TRPV1 | |
| SCHEMBL22138218 | 0.79 | IDO1 (0.33) | SLC18A3IDO1TDO2OPRL1CCR2 | |
| SCHEMBL9862085 | 0.78 | IDH1 (0.36) | — | |
| SCHEMBL21724095 | 0.77 | SLC6A3 (0.41) | SMN1; SMN2MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL7113263 | 0.77 | SLC6A3 (0.41) | SMN1; SMN2MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL5859418 | 0.76 | TRPA1 (0.31) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013118118-A1 | ALPHA-HYDROGEN SUBSTITUTED NITROXYLS AND DERIVATIVES THEREOF AS CATALYSTS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2013-08-15 | — | — | WO | disclosed |
| WO-2012113889-A1 | PROCESSES FOR THE STEREOSELECTIVE PREPARATION OF P-CHIRAL FOUR -COORDINATED PHOSPHORUS BORANE COMPOUNDS AND P-CHIRAL THREE-COORDINATED PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2012-08-30 | — | — | WO | disclosed |
| EP-0751934-B1 | SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORP (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0751934-A1 | SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORPORATION (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995026334-A1 | SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORPORATION (US) | 1995-10-05 | — | — | WO | disclosed |
| EP-0342904-A2 | 2-Hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem | MARION LABORATORIES, INC. (a Delaware corporation) (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0303562-A1 | Process for the preparation of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene) acetic-acid derivatives with a major proportion of E or Z isomer | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-02-15 | — | — | EP | disclosed |