SCHEMBL8083133

SCHEMBL8083133

CCN(CC)CC(O)c1cccc2cc(C)oc12

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.44
CYP1A2 P05177 1/20 0.44
RAD52 P43351 1/20 0.38
MAOA P21397 2/20 0.36
MAOB P27338 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MC4R P32245 1/20 0.32
TSHR P16473 1/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31
KDM4E B2RXH2 1/20 0.31
AOC3 Q16853 1/20 0.31
ACHE P22303 1/20 0.30
HSF1 Q00613 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8082687 0.77 CYP1A2 (0.43) CYP2D6CYP1A2RAD52ALDH1A1MEN1
Hydrochloric Acid SCHEMBL8082698 0.76 CYP1A2 (0.42) CYP2D6CYP1A2RAD52ALDH1A1MEN1
SCHEMBL8081896 0.75 CYP1A2 (0.41) CYP2D6CYP1A2RAD52ALDH1A1MC4R
SCHEMBL8088062 0.75 CYP1A2 (0.41) CYP2D6CYP1A2RAD52ALDH1A1MC4R
SCHEMBL8081964 0.75 CYP1A2 (0.41) CYP2D6CYP1A2RAD52ALDH1A1MC4R
Hydrochloric Acid SCHEMBL8083177 0.74 CYP1A2 (0.40) CYP2D6CYP1A2RAD52ALDH1A1MC4R
Hydrochloric Acid SCHEMBL8083178 0.74 CYP1A2 (0.40) CYP2D6CYP1A2RAD52ALDH1A1MC4R
SCHEMBL18768101 0.73 TSHR (0.46) MAOAMAOBALDH1A1TSHRCRBN
SCHEMBL14377703 0.72 MAOA (0.42) CYP1A2MAOAMAOBALDH1A1TSHR
SCHEMBL7996483 0.71 CYP2D6 (0.43) CYP2D6CYP1A2RAD52ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6063810-A ENANTIOMORPHS SYNTHELABO (FR) 2000-05-16 US disclosed
EP-0888324-A1 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1999-01-07 EP disclosed
WO-1997032870-A1 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF SYNTHELABO (FR) 1997-09-12 WO disclosed