SCHEMBL8083149

SCHEMBL8083149

C/C(=N\c1ccc([N+](=O)[O-])cc1C(C)C)c1cccc(/C(C)=N/c2ccc([N+](=O)[O-])cc2C(C)C)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
PKM P14618 1/20 0.38
LMNA P02545 3/20 0.38
RAB9A P51151 3/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MITF O75030 1/20 0.38
GAA P10253 1/20 0.38
AGTR1 P30556 1/20 0.38
OPRK1 P41145 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
G6PD P11413 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
KMT2A Q03164 4/20 0.36
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2A Q12879 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083153 1.00 MAPT (0.38) MAPTPKMLMNARAB9AALDH1A1
SCHEMBL3921886 0.83 GRIN2D (0.51) MAPTPKMLMNARAB9AALDH1A1
SCHEMBL3921890 0.83 GRIN2D (0.51) MAPTPKMLMNARAB9AALDH1A1
SCHEMBL8085062 0.81 MAPT (0.40) MAPTLMNARAB9AALDH1A1HTT
Hydrochloric Acid SCHEMBL3924751 0.81 GRIN2D (0.49) MAPTLMNARAB9AALDH1A1TDP1
SCHEMBL8085056 0.81 MAPT (0.40) MAPTLMNARAB9AALDH1A1HTT
Hydrochloric Acid SCHEMBL3924753 0.81 GRIN2D (0.49) MAPTLMNARAB9AALDH1A1TDP1
SCHEMBL5588276 0.79 TRPA1 (0.38) MAPTLMNARAB9AALDH1A1KMT2A
SCHEMBL5587396 0.78 TRPA1 (0.37) MAPTLMNARAB9AALDH1A1KMT2A
SCHEMBL8094733 0.78 MAPT (0.35) MAPTLMNARAB9AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1059313-A1 Transition metal catalyst component for polymerization, aromatic vinyl compound-olefin copolymer and process for its production by means of the catalyst component DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-12-13 EP disclosed