Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595225 | 1.00 | TLR4 (0.34) | TLR4USP2ALDH1A1CRBN | |
| SCHEMBL29595955 | 1.00 | TLR4 (0.34) | TLR4USP2ALDH1A1CRBN | |
| SCHEMBL22612531 | 0.86 | KMT2A (0.41) | TLR4ALDH1A1 | |
| SCHEMBL11825966 | 0.83 | TLR4 (0.37) | TLR4CRBN | |
| SCHEMBL7741357 | 0.80 | TLR4 (0.35) | TLR4CRBN | |
| SCHEMBL4548466 | 0.78 | ALDH1A1 (0.38) | TLR4ALDH1A1 | |
| SCHEMBL14595938 | 0.78 | TSHR (0.36) | TLR4ALDH1A1 | |
| SCHEMBL6923072 | 0.78 | ALDH1A1 (0.38) | TLR4ALDH1A1 | |
| SCHEMBL10028630 | 0.77 | TLR4 (0.33) | TLR4ALDH1A1 | |
| SCHEMBL727954 | 0.77 | TLR4 (0.33) | TLR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339278-B1 | NOVEL ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2019-06-12 | — | — | EP | claimed |
| CN-108203382-A | Novel sensory compounds | 国际香料和香精公司 | 2018-06-26 | — | — | CN | claimed |
| EP-0810213-B1 | Organic peroxide stabilization with beta-dicarbonyl or cyclic alpha-diketone compounds | CK WITCO CORP (US) | 2000-09-06 | — | — | EP | claimed |
| CN-108203382-A | Novel sensory compounds | 国际香料和香精公司 | 2018-06-26 | — | — | CN | disclosed |
| US-4049653-A | ANALGESICS, ANTIANXIETY AGENTS | ABBOTT LABORATORIES (US) | 1977-09-20 | — | — | US | disclosed |