SCHEMBL8083293

SCHEMBL8083293

CCCCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1cc(Cl)c(C)c(Cl)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.38
NPSR1 Q6W5P4 5/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
ALDH1A1 P00352 1/20 0.38
ACACB O00763 1/20 0.37
MAPT P10636 4/20 0.34
HTT P42858 3/20 0.34
UBE2N P61088 2/20 0.34
GLA P06280 1/20 0.34
RAD52 P43351 2/20 0.33
APAF1 O14727 1/20 0.33
HSP90AA1 P07900 1/20 0.33
RAB9A P51151 1/20 0.33
NOD2 Q9HC29 1/20 0.33
MITF O75030 1/20 0.32
STAT3 P40763 1/20 0.32
RCE1 Q9Y256 1/20 0.32
RRM1 P23921 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083837 0.97 MAPK1 (0.37) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL8087406 0.97 MAPK1 (0.37) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL8075435 0.95 MAPK1 (0.39) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL7704204 0.91 NPSR1 (0.40) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL8740989 0.91 MAPK1 (0.37) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL11513749 0.86 ACACB (0.37) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL8082860 0.85 KMT2A (0.38) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL11528814 0.85 NPSR1 (0.41) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL11754837 0.84 NPSR1 (0.40) MAPK1NPSR1MEN1KMT2ASMN1; SMN2
SCHEMBL11421800 0.83 MAPK1 (0.39) MAPK1NPSR1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223529-B1 Silver halide light-sensitive element EASTMAN KODAK COMPANY (US) 2007-05-29 US disclosed
US-7223529-B1 Silver halide light-sensitive element EASTMAN KODAK COMPANY (US) 2007-05-29 US disclosed
EP-0608896-B2 Process for producing aromatic amide compounds useful as cyan coupler for color photographs SUMITOMO CHEMICAL CO (JP) 2000-11-02 EP disclosed
US-5442114-A Process for producing aromatic amide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-15 US disclosed
EP-0608896-A1 Process for producing aromatic amide compounds useful as cyan coupler for color photographes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-03 EP disclosed