⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28489036 | 0.97 | — | — | |
| SCHEMBL14227417 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL10919262 | 0.69 | — | — | |
| SCHEMBL3434601 | 0.69 | — | — | |
| SCHEMBL18972158 | 0.67 | — | — | |
| SCHEMBL27377368 | 0.67 | — | — | |
| SCHEMBL1482550 | 0.67 | — | — | |
| SCHEMBL31440713 | 0.67 | LMNA (0.32) | — | |
| SCHEMBL15338442 | 0.67 | — | — | |
| SCHEMBL8074359 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104098587-A | 2, 4-diamino-thieno [2, 3-d] pyrimidine derivative as well as preparation method and application thereof | UNIV CAPITAL NORMAL | 2014-10-15 | — | — | CN | claimed |
| CN-101759654-B | 4-quinazolinone-6-methylamino dithiocarbamate as well as medical composition and application thereof | CAPITAL NORMAL UNIV. (CN) | 2011-12-28 | — | — | CN | claimed |
| CN-101759654-A | 4-quinazolinone-6-methylamino dithiocarbamate as well as medical composition and application thereof | UNIV CAPITAL NORMAL | 2010-06-30 | — | — | CN | claimed |
| CN-116313255-A | Corrosion-resistant cable for data transmission and preparation method thereof | 盐城联翔电子科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-104098587-A | 2, 4-diamino-thieno [2, 3-d] pyrimidine derivative as well as preparation method and application thereof | UNIV CAPITAL NORMAL | 2014-10-15 | — | — | CN | disclosed |
| CN-101759654-B | 4-quinazolinone-6-methylamino dithiocarbamate as well as medical composition and application thereof | CAPITAL NORMAL UNIV. (CN) | 2011-12-28 | — | — | CN | disclosed |
| CN-101759654-A | 4-quinazolinone-6-methylamino dithiocarbamate as well as medical composition and application thereof | UNIV CAPITAL NORMAL | 2010-06-30 | — | — | CN | disclosed |
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| CN-100434425-C | 4-quinazolone derivative and its use in anti-tumor medicine | UNIV CAPITAL NORMAL (CN) | 2008-11-19 | — | — | CN | disclosed |
| CN-1683344-A | 4-quinazolone derivative and its use in anti-tumor medicine | UNIV CAPITAL NORMAL (CN) | 2005-10-19 | — | — | CN | disclosed |