Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089256 | 0.92 | MEN1 (0.44) | BCHEKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL6283431 | 0.87 | L3MBTL1 (0.53) | BCHEKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL8083502 | 0.86 | BCHE (0.49) | BCHEKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL28743621 | 0.85 | BCHE (0.48) | BCHEKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL13168856 | 0.82 | L3MBTL1 (0.50) | BCHEKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL28743659 | 0.82 | KMT2A (0.46) | BCHEKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL20505528 | 0.82 | KMT2A (0.69) | KMT2AMEN1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL28743917 | 0.82 | BCHE (0.45) | BCHEKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL7869160 | 0.82 | CDC25A (0.57) | BCHEKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL10824174 | 0.81 | OXER1 (0.49) | BCHEKMT2AMEN1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555537-B1 | Endothelin antagonists | BANYU PHARMA CO LTD (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |