Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | SCN1A | P35498 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308385 | 1.00 | EBP (0.39) | EBPSIGMAR1CACNA1BCYP3A4ABCB1 | |
| SCHEMBL7309070 | 0.93 | EBP (0.39) | EBPSIGMAR1CACNA1BABCB1 | |
| SCHEMBL7317510 | 0.88 | — | — | |
| SCHEMBL7319271 | 0.88 | SLC22A2 (0.35) | CACNA1BCYP3A4TSHRKCNH2OPRK1 | |
| SCHEMBL7307833 | 0.86 | EBP (0.45) | EBPSIGMAR1CACNA1BCYP3A4ABCB1 | |
| SCHEMBL7306127 | 0.86 | EBP (0.38) | EBPSIGMAR1CACNA1BCYP3A4ABCB1 | |
| SCHEMBL7315987 | 0.86 | EBP (0.38) | EBPSIGMAR1CACNA1BCYP3A4TSHR | |
| SCHEMBL7310617 | 0.86 | EBP (0.38) | EBPSIGMAR1CACNA1BCYP3A4TSHR | |
| SCHEMBL7317409 | 0.85 | EBP (0.39) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7305038 | 0.85 | EBP (0.39) | EBPSIGMAR1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |