Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310617 | 1.00 | EBP (0.38) | EBPSIGMAR1CACNA1BCHRM2CHRM1 | |
| SCHEMBL7308385 | 0.86 | EBP (0.39) | EBPSIGMAR1CACNA1BCHRM2MEN1 | |
| SCHEMBL8083545 | 0.86 | EBP (0.39) | EBPSIGMAR1CACNA1BCHRM2MEN1 | |
| SCHEMBL7306127 | 0.85 | EBP (0.38) | EBPSIGMAR1CACNA1BCYP3A4 | |
| SCHEMBL7309070 | 0.81 | EBP (0.39) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7307833 | 0.77 | EBP (0.45) | EBPSIGMAR1CACNA1BCHRM2CHRM3 | |
| SCHEMBL7316183 | 0.76 | EBP (0.34) | EBPSIGMAR1 | |
| SCHEMBL7317510 | 0.76 | — | — | |
| SCHEMBL7319271 | 0.76 | SLC22A2 (0.35) | CACNA1BCYP3A4KCNH2TSHR | |
| SCHEMBL7308431 | 0.75 | EBP (0.38) | EBPSIGMAR1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |