Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL4766771 | 0.96 | KDM4E (0.58) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Adipic Acid SCHEMBL10713644 | 0.91 | KDM4E (0.53) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Succinic Acid SCHEMBL124833 | 0.91 | KDM4E (0.53) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL8160655 | 0.90 | KDM4E (0.64) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL1683152 | 0.90 | KDM4E (0.64) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Adipic Acid SCHEMBL4371438 | 0.89 | KDM4E (0.55) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Succinic Acid SCHEMBL8083562 | 0.86 | KDM4E (0.49) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL23279 | 0.85 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL30163040 | 0.85 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL23861 | 0.85 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040914-A1 | LAMINATED FILM FOR GLASS SHATTERING PREVENTION | TEIJIN LIMITED (JP) | 2000-10-04 | — | — | EP | disclosed |