Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FES | P07332 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 8/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089921 | 0.86 | MMP8 (0.48) | EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL8098060 | 0.86 | EPHX1 (0.36) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL8098074 | 0.85 | EPHX1 (0.35) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL7442429 | 0.83 | MEN1 (0.50) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL8083610 | 0.82 | MMP8 (0.54) | EPHX2EPHX1NPC1RAB9AKMT2A | |
| SCHEMBL8090095 | 0.82 | KDM4E (0.44) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL30496703 | 0.81 | CHRNA7 (0.53) | HDAC2HDAC8HDAC6RECQLMEN1 | |
| SCHEMBL17198951 | 0.81 | CHRNA7 (0.53) | HDAC2HDAC8HDAC6RECQLMEN1 | |
| Hydrochloric Acid SCHEMBL28128838 | 0.79 | CHRNA7 (0.51) | HDAC2HDAC8HDAC6RECQLMEN1 | |
| SCHEMBL8083456 | 0.79 | MMP8 (0.46) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |